๐ ็ธฝ็ฎ้ ๏ฝ ๐ ่ฑๆๅๆ๏ผๆฌ็ฏ๏ผ ๏ฝ ๐ ๅฎๆด็ฟป่ญฏ ๏ฝ โญ ็ฒพ่ฏ็ญ่จ
Hemostasis
Hemostasis
Hemostasis is essential for wound healing, as the activation of the coagulation cascade and formation of a clot play an essential role in initiating the healing cascade. While hemostasis is an important goal at the end of surgery, some bleeding at the time of dressing and wound care is frequently seen. The main options for hemostasis in open or actively bleeding small wounds are caustic agents, physical agents, and physiological agents. Caustic agents include aluminum chloride, ferric sulfate, silver nitrate, and zinc chloride. These work by local tissue destruction, initiating coagulation and forming a small eschar. Aluminum chloride is most commonly used, and is desirable because it does not leave residual skin pigmentation. Noncaustic agents include physical agents, gelatin, cellulose, p-GlcNAc, and microfibrillar collagen, which promote clot formation by forming a mesh for further clotting. These approaches may promote a granulomatous foreign-body reaction so they should be avoided in settings of infection, or near the eyes in particular. Physiological agents include epinephrine and cocaine, which induce vasoconstriction, as well as topical thrombin, fibrin sealant, or platelet gels.53