๐ ็ธฝ็ฎ้ ๏ฝ ๐ ่ฑๆๅๆ๏ผๆฌ็ฏ๏ผ ๏ฝ ๐ ๅฎๆด็ฟป่ญฏ ๏ฝ โญ ็ฒพ่ฏ็ญ่จ
Intralesional corticosteroids
Intralesional corticosteroids
Intralesional corticosteroid injections are considered first-line therapy for both keloids and hypertrophic scars.42,87 When injected into the skin, steroids decrease fibroblast proliferation and collagen synthesis while reducing inflammatory mediators. Hypertrophic scars are injected every 4 to 6 weeks with 10 mg/mL triamcinolone, depending upon the depth of the scar. Side effects include hypopigmentation, atrophy, and telangiectasias. The success rate for triamcinolone acetonide is more than 50%, with lower recurrence rates.55 Of note, over-treatment with intralesional corticosteroids can cause skin atrophy, and two studies have demonstrated that oral and topical retinoids may alleviate the atrophy associated with scar over-treatment.88,89