๐ ็ธฝ็ฎ้ ๏ฝ ๐ ่ฑๆๅๆ๏ผๆฌ็ฏ๏ผ ๏ฝ ๐ ๅฎๆด็ฟป่ญฏ ๏ฝ โญ ็ฒพ่ฏ็ญ่จ
CRYOTHERAPY
CRYOTHERAPY
A study by Karp et al. evaluated cryotherapy as a modality for acne treatment. In their study, a mixture of solid carbon dioxide, acetone, and precipitated sulfur was applied to a lesion for 20 minutes. This combination led to mild exfoliation, erythema, and edema.10 A comparative study further demonstrated that liquid nitrogen may improve pustular, but not comedonal or papular acne, and is most effective for superficial lesions.11 In addition, liquid nitrogen has been shown to reduce keloid volume in 80% of acne scars, with a combination of cryotherapy and intralesional corticosteroid injections reportedly providing a more significant response.12,13
Cryotherapy is associated with a significant risk of hypopigmentation, and patients should be advised that it may take several weeks for the resulting erythema to resolve.14,15